郝爱连,肖玉鸿,邢晓东,张文云,陈吉华,杨立斗.Bis-GMA/TEGDMA树脂水解产物分析[J].口腔材料器械杂志,2012,21(4):181-186.
Bis-GMA/TEGDMA树脂水解产物分析
Analysis of hydrolysis products of Bis-GMA /TEGDMA resin
投稿时间：2012-03-26  修订日期：2012-06-13
DOI：10.11752/j.kqcl.2012.04.03
中文关键词:  Bis-GMA/TEGDMA树脂  水解  高效液相色谱质谱
英文关键词:Bis-GMA/TEGDMA resin  Hydrolysis  HPLC/MS
基金项目:国家自然科学基金项目(30973356,81130078)
作者单位E-mail
郝爱连 成都军区昆明总医院口腔科昆明医医科大学教学医院, 昆明 650032  
肖玉鸿 成都军区昆明总医院口腔科昆明医医科大学教学医院, 昆明 650032 xiaoyuhong56@126.com 
邢晓东 南京理工大学化工学院, 南京 210094  
张文云 成都军区昆明总医院口腔科昆明医医科大学教学医院, 昆明 650032  
陈吉华 第四军医大学口腔医学院修复科, 西安 710032  
杨立斗 成都军区昆明总医院口腔科昆明医医科大学教学医院, 昆明 650032  
摘要点击次数: 932
全文下载次数: 0
中文摘要:
      目的：检测Bis-GMA/TEGDMA树脂片经去离子水浸泡后的水解产物。方法：Bis-GMA/TEGDMA单体加入CQ/DMAEMA后光照聚合制备树脂片,将树脂片经37℃恒温去离子水浸泡24h,其中在1h、3h、6h和24h四个时间点各取1mL浸泡液,用乙酸乙酯萃取、旋蒸,通过高效液相色谱质谱法(HPLC/MS)检测分析,确定树脂水解产物。结果：树脂片的水解产物为双酚A-二甘油醚(Bis-GMA-2MA)、双酚A-二氧代丙基醚(Bis-GMA-2MA-2H2O)、单甲基丙烯酸二缩三乙二醇酯(TEGDMA-MA)和二缩三乙二醇(TEGDMA-2MA)。结论：Bis-GMA/TEGDMA树脂片经去离子水浸泡后树脂可发生水解,水解产物及残余Bis-GMA/TEGDMA树脂单体可析出并释放到去离子水中。
英文摘要:
      Objective: To detect the hydrolysis products of resin discs immersed in demonized water. Methods: Light-cured resin discs composed of Bis-GMA/TEGDMA and CQ/DMAEMA were immersed in deionized water for 24 h at 37℃,then,1 mL of soak solution at 1 h,3 h,6 h and 24 h was extracted with ethyl acetate and evaporated by a rotary evaporator. Finally the hydrolysis products of resins were confirmed through the high performance liquid chromatography (HPLC) and mass spectrometry (MS). Results: The hydrolysis products of Bis-GMA/TEGDMA resin discs were Bis-GMA-2MA,Bis-GMA-2MA-2H2O,TEGDMA-MA and TEGDMA-2MA,respectively. Conclusions: Bis-GMA/TEGDMA resin was hydrolyzed after immersed in deionized water. The hydrolysis products and residual monomers of Bis-GMA/TEGDMA could be released into deionized water.
查看全文  查看/发表评论  下载PDF阅读器
关闭