| 赵星,汪青风,闫福华,沈振华.All-on-4即刻种植与延期种植对牙列缺失患者恢复情况及对PES评分和炎症因子水平的影响研究[J].口腔材料器械杂志,2022,31(2):147-152. |
| All-on-4即刻种植与延期种植对牙列缺失患者恢复情况及对PES评分和炎症因子水平的影响研究 |
| Effect of immediate and delayed implantation with all-on-4 treatmenton recovery, PES score and inflammatory factor levelsof patients with dentition loss |
| 投稿时间：2020-09-29 修订日期：2020-09-29 |
| DOI：10.11752/j.kqcl.2022.02.16 |
| 中文关键词: 即刻修复 All-on-4 延期修复 PES评分 炎性因子 |
| 英文关键词:Immediate repair All-on-4 Delayed repair PES score Inflammatory factors |
| 基金项目:江苏省条件建设与民生科技专项（编号：BL2013002） |
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| 中文摘要: |
| 目的 研究All-on-4即刻种植与延期种植对牙列缺失患者恢复情况及对PES评分和炎症因子水平的影响。方法 采取前瞻性研究，选择自2018年1月到2019年1月期间在本院进行治疗的牙列缺失患者120例作为研究对象，平均年龄为（45.67±3.09）岁，使用随机数字表将以上患者随机分为两组，每组60例，其中观察组采取All-on-4即刻种植治疗，对照组采取延期种植，比较两组患者术后12个月的治疗效果、PES评分、牙槽嵴骨的吸收高度、主观满意度、龈沟液炎性反应水平、并发症之间的差异。结果 观察组患者的总有效率显著高于对照组（P< 0.05）；经过治疗后，两组患者的PES评分均显著改善，且观察组患者的PES评分高于对照组（P< 0.05）；观察组患者的附着高度、咀嚼功能、整体美观显著优于对照组，牙槽嵴骨的吸收高度显著低于对照组（P< 0.05）；两组患者的IL-4、IL-10、INF-γ以及TNF-α水平显著下降（P< 0.05），且观察组患者的IL-4、IL-10、INF-γ以及TNF-α水平显著低于对照组（P< 0.05）；两组患者的并发症牙龈撕裂、舌侧骨板骨折、术后干槽症之间的差异不存在统计学意义（P> 0.05）。结论 牙列缺失患者的治疗中采取All-on-4即刻种植修复，患者的PES评分显著改善，炎症因子水平显著下降，治疗效果显著。 |
| 英文摘要: |
| Objective The aim of this study was to study the effect of immediate and delayed implantation with all-on-4 implants on recovery, PES score and inflammatory factor levelsof patients with dentition loss. Methods In this prospective study, 120 patients with dentition loss who were treated in our hospital from January 2018 to January 2019 were selected as the research objects, with an average age of (45.67±3.09) years old. The above patients were randomly divided into two groups by random number table:the observation group and the control group, with 60 cases in each group. The observation group was treated with all-on-4 immediate implantation, and the control group was treated with all-on-4 delayed implantation. The treatment effect, PES score, alveolar bone resorption height, subjective satisfaction, gingival crevicular fluid inflammatory reaction level and complications were compared between the two groups. Results The total effective rate of the observation group was significantly higher than that of the control group (P< 0.05). After treatment, the PES scores of the two groups were significantly improved, and the PES scores of the observation group were higher than those of the control group (P< 0.05). The subjective attachment height, masticatory function and overall beauty of the observation group were significantly better than those of the control group, and the alveolar bone absorption height was significantly lower than that of the control group (P< 0.05); The levels of IL-4, IL-10, inf-γ and TNF-α in the two groups were significantly decreased (P< 0.05), and the levels of IL-4, IL-10, INF-γ and TNF-α in the observation group were significantly lower than those in the control group (P< 0.05); there was no significant difference in the complications of gingival tear, lingual bone plate fracture and postoperative dry socket between the two groups (P> 0.05). Conclusion All-on-4 immediate implant restoration was adopted in the treatment of edentulous patients. The PES score of patients was significantly improved, the level of inflammatory factors was significantly decreased, and the treatment effect was significant. |
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